{"title":"All Tests","description":"\u003cp\u003eExplore all Enigma Genomics tests, care packages, genetic counselling and gift cards.\u003c\/p\u003e","products":[{"product_id":"mycancercare","title":"MyCancerCare","description":"\u003cp\u003eMyCancerCare is designed to assess the individual's risk of developing a wide array of cancers (besides breast and colon cancers) and provide detailed screening recommendations to keep them healthy.MyCancerCare can also guide patients who have already developed cancer to choose the best treatment option for their cancer based on their genetic makeup (personalized cancer treatment).\u003c\/p\u003e","brand":"Medical Genetics Company","offers":[{"title":"Saudi National (0% VAT)","offer_id":45260577603870,"sku":"MyCancerCare-Saudi","price":2550.0,"currency_code":"SAR","in_stock":true},{"title":"Non-Saudi National (15% VAT included)","offer_id":45260577669406,"sku":"MyCancerCare-NonSaudi","price":2932.5,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/MyCancerCare-03-kit-concept_afce6740-ba3a-4eeb-9b62-d38ec7440bab.webp?v=1793563703"},{"product_id":"mygenomecare","title":"MyGenomeCare","description":"\u003cp\u003eMyGenomeCare is the ultimate tool to understand your genetic information and obtain precise recommendations to keep you healthy as you navigate the journey of life. MyGenomeCare is a comprehensive way of analyzing the entire human genome providing a very high-resolution view of all genetic information. In addition to testing all the known Genes, MyGenomeCare also analyzes the rest of the human genome (called non-coding regions), which can influence numerous adult-onset diseases such as obesity, diabetes, and high blood pressure.\u003c\/p\u003e","brand":"Medical Genetics Company","offers":[{"title":"Saudi National (0% VAT)","offer_id":45266603016478,"sku":"MyGenomeCare-Saudi","price":4650.0,"currency_code":"SAR","in_stock":true},{"title":"Non-Saudi National (15% VAT included)","offer_id":45266603049246,"sku":"MyGenomeCare-NonSaudi","price":5347.5,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/MyGenomeCare-03-kit-concept_2286e538-ccbd-4bac-b14c-ad3f9ed38b0e.webp?v=1793563808"},{"product_id":"mymarriagecare","title":"MyMarriageCare","description":"\u003cp\u003eUp to 90% of healthy individuals carry one or more “bad” genetic variants that can potentially cause genetic diseases in their children. The national premarital screening program only tests for two of several hundred genetic conditions relatively common in the region. MyPremaritalCare provides prospective couples with a comprehensive assessment of their genetic carrier status with detailed recommendations on how to ensure the well-being of their future children.\u003c\/p\u003e","brand":"Medical Genetics Company","offers":[{"title":"Saudi National (0% VAT)","offer_id":45266599837982,"sku":"MyMarriageCare-Saudi","price":2550.0,"currency_code":"SAR","in_stock":true},{"title":"Non-Saudi National (15% VAT included)","offer_id":45266599870750,"sku":"MyMarriageCare-NonSaudi","price":2932.5,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/MyMarriageCare-03-kit-concept.webp?v=1793563823"},{"product_id":"mychildcare","title":"MyChildCare","description":"\u003cp\u003eIt takes up to 8 years to diagnose children with rare complex genetic diseases. By the time the diagnosis is reached, the health of these patients has typically considerably deteriorated. Therefore, the American College of Medical Genetics and Genomics recommends using whole-exome sequencing as a first-tier test for children with complex genetic diseases. MyChildCare is designed to test all Genes at once, thus representing a quick and effective way to establish the diagnosis in a timely manner.\u003c\/p\u003e","brand":"Medical Genetics Company","offers":[{"title":"Saudi National (0% VAT)","offer_id":45266654265630,"sku":"MyChildCare-Saudi","price":2950.0,"currency_code":"SAR","in_stock":true},{"title":"Non-Saudi National (15% VAT included)","offer_id":45266654298398,"sku":"MyChildCare-NonSaudi","price":3392.5,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/MyChildCare-03-kit-concept.webp?v=1793563793"},{"product_id":"myobesitycare","title":"MyObesityCare","description":"\u003cp\u003eThe Monogenic Obesity Panel analyzes Genes associated with severe and early-onset obesity, which may be isolated due to endocrine abnormalities or associated with syndromic features. This panel may be appropriate for individuals with hyperphagia and endocrine dysfunction and individuals with obesity and phenotypic changes consistent with a syndromic etiology. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential Genes based on a single clinical indication.\u003c\/p\u003e","brand":"Medical Genetics Company","offers":[{"title":"Saudi National (0% VAT)","offer_id":45257879257374,"sku":"MyObesityCare-Saudi","price":2550.0,"currency_code":"SAR","in_stock":true},{"title":"Non-Saudi National (15% VAT included)","offer_id":45257879290142,"sku":"MyObesityCare-NonSaudi","price":2932.5,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/MyObesityCare-03-kit-concept_14df2640-3865-483f-a66b-c2efcfe2af76.webp?v=1793563829"},{"product_id":"egcanall","title":"Comprehensive Cancer Panel","description":"The Comprehensive Cancer Panel analyzes 109 genes associated with hereditary cancers across major organ systems, including:\n\n\nbreast and gynecologic (breast, ovarian, uterine)\ngastrointestinal (colorectal, gastric, pancreatic)\nendocrine (thyroid, paraganglioma\/pheochromocytoma, parathyroid, pituitary)\ngenitourinary (renal\/urinary tract, prostate)\nskin (melanoma, basal cell carcinoma)\nbrain\/nervous system\nsarcoma\nhematologic (myelodysplastic syndrome\/leukemia)\n\nThe Comprehensive Cancer Panel is designed to maximize diagnostic yield for individuals with a personal or family history of mixed cancers affecting multiple organ systems. \n\n\nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. Heterozygous Pathogenic\/Likely pathogenic germline variants in RAD50 and NBN are not clearly associated with an increased risk for cancer; however, such variants may qualify certain patients for clinical trials targeting homologous recombination deficient tumors. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150025502,"sku":"EGCANALL","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-ribbon-v1.png?v=1793570962"},{"product_id":"egcanbov","title":"Breast and Ovarian Cancer Panel","description":"The Breast and Ovarian Cancer Panel analyzes genes that are associated with hereditary predisposition to breast, ovarian, and endometrial\/uterine cancers. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for hereditary breast and gynecologic cancers. Given the clinical overlap of hereditary susceptibility to breast and gynecologic cancers, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. Genetic testing of these genes may help confirm a clinical diagnosis, help predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150058270,"sku":"EGCANBOV","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-ribbon-v1.png?v=1793570962"},{"product_id":"egcancrc","title":"Colorectal Cancer Panel","description":"The Colorectal Cancer Panel analyzes genes associated with a hereditary predisposition to colorectal cancer. These genes were selected based on the available evidence to date to provide the broadest test for colorectal cancer.\n\nIn addition to the primary panel, several genes have been included to cover preliminary evidence for cancer predisposition. These genes were selected from a review of the literature and expert recommendations. \nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150091038,"sku":"EGCANCRC","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-intestine-v1.png?v=1793570970"},{"product_id":"egcanlun","title":"Lung Cancer Panel","description":"The Lung Cancer Panel analyzes genes that are associated with hereditary predispositions to lung cancers. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for hereditary lung cancers. Given the clinical overlap of various cancer phenotypes, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. Genetic testing of these genes may help confirm a clinical diagnosis, help predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150123806,"sku":"EGCANLUN","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-lungs-v1.png?v=1793570976"},{"product_id":"egcangas","title":"Gastric Cancer Panel","description":"The Gastric Cancer Panel analyzes genes associated with an increased lifetime risk of developing stomach cancer. These genes were selected based on the available evidence to date to provide the broadest hereditary gastric cancer test. Many of these genes are also associated with an increased risk of other cancer types.\nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150156574,"sku":"EGCANGAS","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-stomach-v1.png?v=1793570983"},{"product_id":"egcanpan","title":"Pancreatic Cancer Panel","description":"The Pancreatic Cancer Panel analyzes genes that are associated with a hereditary predisposition for pancreatic cancer. These genes were selected based on the available evidence to date to provide the broadest test for hereditary pancreatic cancer. \nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150189342,"sku":"EGCANPAN","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-pancreas-v1.png?v=1793570990"},{"product_id":"egcanskn","title":"Melanoma\/Skin Cancer Panel","description":"The Melanoma\/Skin Cancer Panel analyzes genes associated with a hereditary predisposition to melanoma. These genes were selected based on available evidence to provide the most comprehensive test targeting hereditary melanoma. Given the clinical overlap of hereditary susceptibility to skin cancers, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. \nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150222110,"sku":"EGCANSKN","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-skin-v1.png?v=1793570996"},{"product_id":"egcanpca","title":"Prostate Cancer Panel","description":"The Prostate Cancer Panel analyzes genes associated with a hereditary predisposition to prostate cancer. These genes were selected based on the available evidence to date to provide the most comprehensive test for hereditary prostate cancer. Given the clinical overlap of hereditary susceptibility to prostate cancer, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. \n\nGenetic testing may confirm a clinical diagnosis and guide treatment and management decisions. At-risk relatives may also be identified, allowing the pursuit of a diagnostic evaluation, early detection, and improved clinical outcome. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150254878,"sku":"EGCANPCA","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-cell-v1.png?v=1793571004"},{"product_id":"egcanend","title":"Endometrial Cancer Panel","description":"The Endometrial Cancer Panel analyzes genes associated with a hereditary predisposition to endometrial cancer. These genes were selected based on the available evidence to date to provide the most comprehensive test for hereditary endometrial cancer. Given the clinical overlap of hereditary susceptibility to endometrial cancer, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. \n\nGenetic testing may confirm a clinical diagnosis and guide treatment and management decisions. At-risk relatives may also be identified, allowing the pursuit of a diagnostic evaluation, early detection, and improved clinical outcome. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150320414,"sku":"EGCANEND","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-uterus-v1.png?v=1793571011"},{"product_id":"egcanped","title":"Pediatric Cancer Panel","description":"The Pediatric Cancer Panel analyzes genes that are associated with the development of malignant and benign tumors throughout the body. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for hereditary predisposition to childhood solid tumors. Given the clinical overlap of pediatric solid tumors, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. \n\nGenetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150385950,"sku":"EGCANPED","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-baby-v1.png?v=1793571061"},{"product_id":"egcansom","title":"Comprehensive Tumor Profiling","description":"The Comprehensive Tumor Profiling offers comprehensive genomic profiling for solid tumors using a sequencing (NGS)-based assay that analyzes 484 genes for clinically important alterations at the DNA level. This test interrogates the complete coding regions of 468 genes and the introns of 43 genes for all four types of genomic abnormalities: SNV, InDel, CNV and fusion. These genes are known to be relevant for the diagnosis and\/or treatment of various solid tumors according to National Comprehensive Cancer Network (NCCN) Guidelines and the medical literature. The mutation status of some of these genes can guide the potential application of multiple FDA-approved targeted and\/or immunotherapies as shown Diseases Tested list. The other genes are also analyzed for their relevance to the diagnosis and\/or treatment of various solid tumors according to the medical literature. The report generated provides tailored treatment recommendations for your patients. This test should be used to analyze solid tumors only and has not been optimized for hematological malignancies. \n\nThe clinical interpretation of detected mutations in those genes is done according to our comprehensive in-house oncology knowledgebase constructed based on public resources including GeneCards, CKB, OncoKB, COSMIC, ClinVar PMC, Drugs@FDA, Drug Information Portal (NIH), Selleck, PharmGKB, DGIdb, DRUGBANK, Drugs.com, ClinicalTrials.gov, ICTRP, ChiCTR, KEGG and Cell Signaling. \n\nLimit of Detection (LOD):\nThe LoD of SNV\/InDel detection is 1% mutation allele frequency (MAF) for tissue samples (detection rate = 96.6%) and 0.5% MAF for ctDNA samples (detection rate = 100%).\nThe LoD of ERBB2 CNV detection is 20% tumor cell content for tissue samples (detection rate = 100%) and 5% tumor cell content for ctDNA samples (detection rate = 100%).\nThe LoD of ROS1 and ALK fusion detection is 20% tumor cell content for tissue samples (detection rate = 100%) and 1.25% tumor cell content for ctDNA samples (detection rate = 100%).\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150418718,"sku":"EGCANSOM","price":4950.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-cell-v1.png?v=1793571004"},{"product_id":"egcancfd","title":"Comprehensive cfDNA Profiling","description":"Comprehensive cfDNA Profiling offers comprehensive genomic profiling for solid tumors using a sequencing (NGS)-based assay that analyzes 484 genes for clinically important alterations at the DNA level. This test interrogates the complete coding regions of 468 genes and the introns of 43 genes for all four types of genomic abnormalities: SNV, InDel, CNV and fusion and also generate results (TMB, bTMB and MSI) that can help guide clinical management. These genes are known to be relevant for the diagnosis and\/or treatment of various solid tumors according to National Comprehensive Cancer Network (NCCN) Guidelines and the medical literature. The mutation status of some of these genes can guide the potential application of multiple FDA-approved targeted and\/or immunotherapies as shown Diseases Tested list. The other genes are also analyzed for their relevance to the diagnosis and\/or treatment of various solid tumors according to the medical literature. The report generated provides tailored treatment recommendations for your patients. This test should be used to analyze solid tumors only and has not been optimized for hematological malignancies. \n\nThe clinical interpretation of detected mutations in those genes is done according to our comprehensive in-house oncology knowledgebase constructed based on public resources including GeneCards, CKB, OncoKB, COSMIC, ClinVar PMC, Drugs@FDA, Drug Information Portal (NIH), Selleck, PharmGKB, DGIdb, DRUGBANK, Drugs.com, ClinicalTrials.gov, ICTRP, ChiCTR, KEGG and Cell Signaling. \n\n\nLimit of Detection (LOD):\nThe LoD of SNV\/InDel detection is 1% mutation allele frequency (MAF) for tissue samples (detection rate = 96.6%) and 0.5% MAF for ctDNA samples (detection rate = 100%).\nThe LoD of ERBB2 CNV detection is 20% tumor cell content for tissue samples (detection rate = 100%) and 5% tumor cell content for ctDNA samples (detection rate = 100%).\nThe LoD of ROS1 and ALK fusion detection is 20% tumor cell content for tissue samples (detection rate = 100%) and 1.25% tumor cell content for ctDNA samples (detection rate = 100%).\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150451486,"sku":"EGCANCFD","price":4950.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-oncology-drop-v1.png?v=1793571068"},{"product_id":"egcrrall","title":"Comprehensive Carrier Screen","description":"The Comprehensive Carrier Screen is appropriate for patients who want an expanded assessment of their risk of having a child affected by a genetic condition. \n\nThis panel includes:\nDisorders recommended by the American College of Obstetricians and Gynecologists (ACOG) and the American College of Medical Genetics (ACMG)\nDisorders that may have a severe presentation\nA selection of disorders found on the newborn screen\nSeveral X-linked disorders\n\nPlease see the Disorders Tested for a complete list of disorders tested.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150484254,"sku":"EGCRRALL","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-obstetrics-carrier-v1.png?v=1793571074"},{"product_id":"egcrrprm","title":"Premarital Genetic Panel","description":"The Premarital Genetic Panel is appropriate for patients who want an expanded assessment of their risk of having a child affected by a genetic condition. This test panel is similar to the Comprehensive Carrier Screen but includes additional recommendations specific to partner screening.  \n\nThis panel includes:\nDisorders recommended by the American College of Obstetricians and Gynecologists (ACOG) and the American College of Medical Genetics (ACMG)\nDisorders that may have a severe presentation\nA selection of disorders found on the newborn screen\nSeveral X-linked disorders\n\nPlease see the Disorders Tested for a complete list of disorders tested. \n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150517022,"sku":"EGCRRPRM","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-obstetrics-couple-v1.png?v=1793571081"},{"product_id":"egcarall","title":"Comprehensive Cardiac Panel","description":"The Comprehensive Cardiac Panel provides a comprehensive analysis of the genes associated with inherited arrhythmia and cardiomyopathy conditions. Given the clinical overlap between different arrhythmia and cardiomyopathy conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \nIndividuals with clinical symptoms of an inherited arrhythmia or cardiomyopathy may benefit from genetic testing to establish or confirm the diagnosis, clarify risks, or inform management. Asymptomatic individuals within a family with a known pathogenic variant may also benefit by avoiding activities and medications that can trigger symptoms.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150549790,"sku":"EGCARALL","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-cardiology-heart-v1.png?v=1793571087"},{"product_id":"egcarcmp","title":"Cardiomyopathy Panel","description":"The Cardiomyopathy Panel provides a comprehensive analysis of the genes associated with inherited cardiomyopathy conditions. Given the clinical overlap between different cardiomyopathy conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication.\nIndividuals with clinical symptoms of inherited cardiomyopathy may benefit from diagnostic genetic testing to establish or confirm the diagnosis, clarify risks, or inform management. Asymptomatic individuals within a family with a known pathogenic variant may also benefit by avoiding activities and medications that can trigger symptoms.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150582558,"sku":"EGCARCMP","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-cardiology-heart-v1.png?v=1793571087"},{"product_id":"egcararr","title":"Arrhythmia Panel","description":"The Arrhythmia Panel provides a comprehensive analysis of the genes associated with inherited arrhythmia conditions. This panel also analyzes genes associated with certain syndromic conditions where arrhythmia is a clinical feature. Given the clinical overlap between different arrhythmia conditions, comprehensive testing allows for a more efficient evaluation of multiple conditions based on a single indication for testing.\nIndividuals with clinical symptoms of an inherited arrhythmia may benefit from diagnostic genetic testing to establish or confirm the diagnosis, clarify risks, or inform management. Asymptomatic individuals within a family with a known pathogenic variant may also benefit by avoiding activities and medications that can trigger symptoms.\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150615326,"sku":"EGCARARR","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-cardiology-ecg-v1.png?v=1793571093"},{"product_id":"egcarctd","title":"Aortopathy Panel","description":"The Aortopathy Panel is a comprehensive analysis of genes associated with inherited aortopathy and related conditions.  Enigma's Aortopathy Comprehensive Panel includes genes that are associated with isolated thoracic aortic aneurysms and dissections (TAAD) and multi-system disorders that may have aortopathy as one feature. Given the clinical overlap between different aortopathy conditions, comprehensive testing enables a more efficient evaluation of multiple disorders based on a single indication.\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150648094,"sku":"EGCARCTD","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-cardiology-aorta-v1.png?v=1793571099"},{"product_id":"egcarlpd","title":"Comprehensive Lipidemia Panel","description":"The Comprehensive Lipidemia Panel provides a comprehensive analysis of genes associated with a variety of inherited lipidemias. Lipidemias are characterized by abnormal levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and\/or triglycerides. Abnormal lipid levels increase the risk for cardiovascular events and can cause additional clinical complications. \n\nEarly and appropriate medical intervention can reduce the risk of cardiovascular events. At-risk relatives could be identified, and preventive therapy could be initiated. Given the clinical overlap between different lipidemias, comprehensive testing enables a more efficient evaluation of multiple disorders based on a single indication. \n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150680862,"sku":"EGCARLPD","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-cardiology-blood-v1.png?v=1793571106"},{"product_id":"egcarchd","title":"Congenital Heart Defects Panel","description":"The Congenital Heart Defects Panel analyzes genes that are associated with congenital heart defects (isolated and syndromic) and\/or laterality defects, including heterotaxy and situs inversus. These genes were selected based on currently available evidence and make up the most comprehensive test for congenital heart defects.\n\n\nThis panel also includes genes associated with primary ciliary dyskinesia (PCD). There is significant clinical overlap between heterotaxy, PCD, and congenital heart defects, and it may be difficult to differentiate between these types of heart defects early in life.\n\n\nThis test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150713630,"sku":"EGCARCHD","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-cardiology-heart-v1.png?v=1793571087"},{"product_id":"egimudef","title":"Primary Immunodeficiency Panel","description":"The Primary Immunodeficiency Panel analyzes genes that are associated with inherited disorders of the immune system. These genes were selected based on the available evidence to date and comprise the broadest test for primary immunodeficiencies (PIDs).\nGiven the clinical overlap between different immunodeficiency conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nThis test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150746398,"sku":"EGIMUDEF","price":2400.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-immunology-shield-v1.png?v=1793571132"},{"product_id":"egimuaut","title":"Autoimmune Disorders Panel","description":"The Autoimmune Disorders Panel analyzes genes that are associated with autoinflammatory and autoimmune conditions. Autoinflammatory disorders are characterized by episodic inflammation due to inappropriate activation of the innate immune response, whereas autoimmune disorders are caused by defects in adaptive immunity leading to loss of self-tolerance. Autoimmune and autoinflammatory diseases share clinical manifestations including self-directed inflammation in the absence of a known trigger. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nThis test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150779166,"sku":"EGIMUAUT","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-immunology-shield-v1.png?v=1793571132"},{"product_id":"egimucpt","title":"Complement Deficiency Panel","description":"The Complement Deficiency Panel analyzes genes that are associated with complement disorders. Complement disorders are characterized by increased risk for certain infections, autoimmune disease, atypical hemolytic uremic syndrome, or recurrent episodes of angioedema. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nThis test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150811934,"sku":"EGIMUCPT","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-immunology-cell-v1.png?v=1793571140"},{"product_id":"eghembmf","title":"Bone Marrow Failure Panel","description":"The Bone Marrow Failure Panel analyzes genes that are associated with bone marrow failure (BMF), a condition in which the body is unable to produce enough healthy blood cells. The genetic heterogeneity associated with BMF syndromes can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for BMF. Given the clinical overlap of BMF syndromes, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Genetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations.\nIf the patient has undergone an allogeneic bone marrow or stem cell transplant prior to genetic testing or currently has a hematological condition with actively circulating tumor cells, testing a sample type that is not derived from blood (such as cultured fibroblasts from a skin biopsy) is warranted. \n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150844702,"sku":"EGHEMBMF","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-hematology-bone-v1.png?v=1793571147"},{"product_id":"eghemthb","title":"Thrombophilia Panel","description":"The Thrombophilia Panel analyzes genes that are associated with hereditary thrombophilia. Hereditary thrombophilia is characterized by increased clotting tendency and increased risk for deep venous thrombosis and\/or venous thromboembolism. This test does not include full sequencing for the F2 and F5 genes and only specific variants associated with prothrombin-related thrombophilia and factor V Leiden-related thrombophilia are analyzed. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nThis test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150877470,"sku":"EGHEMTHB","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-hematology-blood-v1.png?v=1793571154"},{"product_id":"eghemptt","title":"Platelet Disorders Panel","description":"The Platelet Disorders Panel analyzes genes associated with disorders of platelet number or function. These disorders are typically characterized by bleeding symptoms which may include excessive bruising, purpura, excessive bleeding after surgery or trauma, nosebleeds, superficial bleeding into the skin (petechiae), and menorrhagia in women. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nThis test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures.\n\nThe GP1BB gene is not offered on this panel. In addition, sequencing for the GP1BA gene is limited to 11 variants.\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150910238,"sku":"EGHEMPTT","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-hematology-platelets-v1.png?v=1793571161"},{"product_id":"eghemred","title":"Hemolytic Anemia Panel","description":"The Hemolytic Anemia Panel analyzes genes that are associated with congenital dyserythropoietic anemia, red blood cell enzymopathies, red blood cell membrane disorders, complement mediated hemolytic anemia, erythrocytosis, methemoglobinemia, and heme oxygenase deficiency. These conditions are characterized by anemia, abnormal red blood cell shape or quantity, jaundice, hematuria, iron overload, and in some cases lymphadenopathy, hepatosplenomegaly, and gallstones. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nThis test may establish a genetic diagnosis, which would eliminate the need for serial gene testing. A genetic diagnosis may guide medical management, enabling a clinician to determine the need for additional evaluations, screenings, and procedures.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974150975774,"sku":"EGHEMRED","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-hematology-blood-v1.png?v=1793571154"},{"product_id":"egmetnbs","title":"Newborn Screening Panel","description":"The Newborn Screening Panel analyzes genes associated with metabolic conditions present in national and international newborn screening (NBS) programs. This panel may be appropriate for symptomatic infants, premature infants, or babies in the neonatal intensive care unit where confounding factors, such as liver immaturity or total parenteral nutrition, cause an increased chance of ambiguous screening results on traditional, biochemical-based testing. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nGenetic testing of these genes may confirm a suspected diagnosis and help guide treatment and management decisions.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151074078,"sku":"EGMETNBS","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-metabolism-baby-v1.png?v=1793571169"},{"product_id":"egmetnbf","title":"Focused Newborn Screening Panel","description":"The Focused Newborn Screening Panel analyzes genes associated with metabolic conditions present in the Saudi newborn screening (NBS) program. This panel may be appropriate for symptomatic infants, premature infants, or babies in the neonatal intensive care unit where confounding factors, such as liver immaturity or total parenteral nutrition, cause an increased chance of ambiguous screening results on traditional, biochemical-based testing. \n\nGenetic testing of these genes may confirm a suspected diagnosis and help guide treatment and management decisions.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151139614,"sku":"EGMETNBF","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-metabolism-baby-v1.png?v=1793571169"},{"product_id":"egmethyp","title":"Hypoglycemia Panel","description":"The Hypoglycemia Panel is indicated for patients with recurrent episodes of low blood glucose (hypoglycemia). Symptoms of hypoglycemia include sweating, weakness, tremor, and vomiting. If untreated, it can lead to seizures, confusion, irritability, coma, and death. Given the clinical overlap between these conditions, comprehensive testing enables a more efficient evaluation of multiple conditions based on a single indication for testing. \n\nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151205150,"sku":"EGMETHYP","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-metabolism-glucose-v1.png?v=1793571175"},{"product_id":"egmetnur","title":"Neurotransmitter Disorders Panel","description":"The Neurotransmitter Disorders Panel analyzes genes that are associated with disorders of neurotransmitter metabolism, receptors, and transporters including:\n\n- Disorders of monoamine synthesis, transport, or metabolism\n- BH4 synthesis\/recycling defects\n- Disorders of GABA synthesis, transport or metabolism, and GABA receptors\n- Defects in glutamate metabolism, receptor, or transporter that affect the central nervous system\n- Vitamin B6 \/ Pyridoxine disorders\n- Disorders of glycine metabolism with effect on the central nervous system, including glycine cleavage system\n- Serine biosynthesis disorders\n\nThis panel may be appropriate for patients with abnormal findings on CSF neurotransmitter studies and\/or neurological features that include a combination of dystonia, parkinsonism, autonomic and behavioral dysfunction, or oculogyric crises. \n\nThese genes were selected based on the available evidence to date to provide a broad test for neurotransmitter disorders. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant could also guide testing and diagnosis of at-risk relatives.\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151303454,"sku":"EGMETNUR","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-metabolism-neuron-v1.png?v=1793571181"},{"product_id":"egnphall","title":"Comprehensive Renal Disease Panel","description":"The Comprehensive Renal Disease Panel analyzes genes that are associated with renal disorders, including but not limited to Alport syndrome, focal segmental glomerulosclerosis (FSGS), nephrotic syndrome, renal tubular disorders, as well as syndromic conditions, which include renal disease or renal anomalies as a clinical feature. Renal disorders are genetically heterogeneous disorders representing a wide spectrum of hereditary renal conditions. The genetic heterogeneity associated with these renal conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. \n\nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. Some genes in this test may be associated with additional disorders unrelated to this panel; such additional conditions are not included in the list of disorders tested.\n\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151434526,"sku":"EGNPHALL","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-nephrology-kidneys-v1.png?v=1793570926"},{"product_id":"egnphrta","title":"Renal Tubular Disorders Panel","description":"The Renal Tubular Disorders Panel analyzes genes that are associated with renal tubular disorders, which are characterized by impaired function and\/or abnormal development of the renal tubules. These genes were selected based on the available evidence to date to provide a broad analysis of inherited renal tubular disorders. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. \n\nIdentification of a disease-causing variant can inform recurrence-risk assessment and genetic counseling. Some genes in this test may be associated with additional disorders unrelated to this panel; such additional conditions are not included in the list of disorders tested.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151532830,"sku":"EGNPHRTA","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-nephrology-kidneys-v1.png?v=1793570926"},{"product_id":"egnphstn","title":"Nephrolithiasis Panel","description":"The Nephrolithiasis Panel analyzes genes that are associated with kidney stones. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions.  ","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151598366,"sku":"EGNPHSTN","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-nephrology-stone-v1.png?v=1793570932"},{"product_id":"egnphcys","title":"Cystic Kidney Disease Panel","description":"Cystic Kidney Disease Panel analyzes genes associated with cystic kidney disease, including but not limited to Alport syndrome, focal segmental glomerulosclerosis (FSGS), and nephrotic syndrome. Cystic kidney conditions are genetically heterogeneous disorders representing a spectrum of hereditary renal conditions. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication.\n\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151696670,"sku":"EGNPHCYS","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-nephrology-kidneys-v1.png?v=1793570926"},{"product_id":"egneuals","title":"Amyotrophic Lateral Sclerosis Panel","description":"The Amyotrophic Lateral Sclerosis Panel analyzes genes that are associated with amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative condition involving the loss of upper and lower motor neurons. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for ALS. Given the clinical overlap of ALS, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. \n\nGenetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.\n\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974151958814,"sku":"EGNEUALS","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-nerve-v1.png?v=1793571232"},{"product_id":"egneunur","title":"Neuropathies Panel","description":"The Neuropathies Panel analyzes genes that are associated with hereditary neuropathies, including but not limited to Charcot-Marie-Tooth disease (CMT), hereditary motor neuropathy (HMN), and hereditary sensory and autonomic neuropathy (HSAN). The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for hereditary neuropathies. Given the clinical overlap of hereditary neuropathies, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. \n\nSome genes in this test may also be associated with additional unrelated disorders which are not included in the list of disorders tested. Genetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152024350,"sku":"EGNEUNUR","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-nerve-v1.png?v=1793571232"},{"product_id":"egneucps","title":"Cerebral Palsy Panel","description":"The Cerebral Palsy Panel analyzes a broad panel of genes to determine the underlying etiology of cerebral palsy (CP), which is a heterogeneous group of neurodevelopmental conditions characterized by abnormal movements and fluctuating patterns of muscle tone and posture. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. \n\nThis panel also includes genes associated with adult-onset neurologic conditions, including HSPs, SCAs, and ALS, as well as the ATM gene for Ataxia-telangiectasia that confers an increased risk for malignancy, particularly leukemia and lymphoma.\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152122654,"sku":"EGNEUCPS","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-brain-v1.png?v=1793571240"},{"product_id":"egneuepi","title":"Epilepsy Panel","description":"The Epilepsy Panel analyzes genes that are associated with both syndromic and nonsyndromic causes of epilepsy, a common neurological disease characterized by recurrent, unprovoked seizures. These genes were curated based on the available evidence to date in order to provide analysis for epilepsy. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. Genetic testing of these genes may help confirm a clinical diagnosis, help predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152319262,"sku":"EGNEUEPI","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-neuron-v1.png?v=1793571246"},{"product_id":"egneuaut","title":"Learning disability and Autism Panel","description":"The Learning disability and Autism Panel analyzes genes that are associated with developmental delay, intellectual disability, and autism spectrum disorder. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for neurodevelopmental disorders. Given the clinical overlap of these conditions, broad panel testing allows for an efficient evaluation of many potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. \n\nGenetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152417566,"sku":"EGNEUAUT","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-brain-v1.png?v=1793571240"},{"product_id":"egneudem","title":"Parkinson, Alzheimer, and Dementia Panel","description":"The Parkinson, Alzheimer, and Dementia Panel analyzes genes that are associated with progressive neurodegenerative conditions affecting the nervous system, including but not limited to amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), Alzheimer disease, Parkinson Disease, and Parkinsonism. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for hereditary dementia and ALS. Given the clinical overlap of hereditary dementia and ALS, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. \n\nGenetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152483102,"sku":"EGNEUDEM","price":2300.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-brain-v1.png?v=1793571240"},{"product_id":"egneunms","title":"Neuromuscular Disorders Panel","description":"The Neuromuscular Disorders Panel analyzes genes that are associated with hereditary neuromuscular conditions, including but not limited to muscular dystrophies, inherited myopathies, mitochondrial disorders, congenital myasthenic syndromes, and rhabdomyolysis. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for neuromuscular disorders. Given the clinical overlap of hereditary neuromuscular disorders, broad panel testing allows for an efficient evaluation of many potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated conditions, which are not included in the list of conditions tested. \n\nGenetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.\n\nThis assay does not currently test for facioscapulohumeral muscular dystrophy type 1 (FSHD1), oculopharyngeal muscular dystrophy (OPMD), or myotonic dystrophy types 1 and 2. Additional testing for these conditions should be considered, if not yet performed and clinically appropriate.\n\n","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152548638,"sku":"EGNEUNMS","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-muscle-v1.png?v=1793571253"},{"product_id":"egneumlf","title":"Brain Malformations Panel","description":"The Brain Malformations Panel analyzes genes that are associated with brain malformations, a collection of disorders of nervous system development that affect the shape and function of the brain. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. These genes were curated based on the available evidence to date in order to provide analysis for brain malformations. Given the clinical overlap of brain malformations, broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Some genes in this test may also be associated with additional unrelated disorders, which are not included in the list of disorders tested. \n\nGenetic testing of these genes may help confirm a clinical diagnosis, predict disease prognosis and progression, facilitate early detection of symptoms, inform family planning and genetic counseling, or promote enrollment in clinical trials.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152614174,"sku":"EGNEUMLF","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-neurology-brain-v1.png?v=1793571240"},{"product_id":"egendmdm","title":"Monogenic Diabetes Panel","description":"Monogenic Diabetes Panel analyzes genes associated with syndromic and nonsyndromic causes of monogenic diabetes. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. \n\nGenetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. Some genes in this test may be associated with additional disorders unrelated to this panel; such additional conditions are not included in the list of disorders tested.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152679710,"sku":"EGENDMDM","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-endocrinology-glucose-v1.png?v=1793571260"},{"product_id":"egendhhg","title":"Hypogonadotropic Hypogonadism Panel","description":"The Hypogonadotropic Hypogonadism Panel analyzes genes that are associated with isolated gonadotropin-releasing hormone deficiency (IGD), Kallmann syndrome, and syndromes with hypogonadism as a presenting feature. These disorders result in low concentrations of gonadotropins (luteinizing and follicle-stimulating hormones) and hypogonadism. Some individuals with IGD have an impaired sense of smell; this combination of features is known as Kallmann syndrome. These genes were selected based on the available evidence to date to provide a broad analysis for inherited hypogonadotropic hypogonadism. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. \n\nIdentification of a disease-causing variant can inform recurrence-risk assessment and genetic counseling.","brand":"Medical Genetics Company","offers":[{"title":"Default Title","offer_id":44974152778014,"sku":"EGENDHHG","price":2550.0,"currency_code":"SAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-endocrinology-hormone-v1.png?v=1793571266"}],"url":"https:\/\/shop.enigmagenomics.com\/en\/collections\/all-tests.oembed?page=6","provider":"Enigma Genomics","version":"1.0","type":"link"}