{"product_id":"eghlafull","title":"HLA Complete Typing: Class I \u0026 II","description":"\u003cp\u003eOverview\u003cbr\u003eHLA Typing High Resolution is a molecular genetic test that identifies the HLA alleles of an individual at six clinically important loci: HLA-A, HLA-B, HLA-C (Class I) and HLA-DRB1, HLA-DQB1, HLA-DPB1 (Class II). The HLA genes are located on chromosome 6p21 (MHC region) and are among the most polymorphic genes in the human genome. They play a central role in immune recognition and in distinguishing self from non-self.\u003c\/p\u003e\u003cp\u003eMethodology\u003cbr\u003eThe test uses DNA extracted from the patient’s sample, followed by targeted amplification of the HLA loci and next-generation sequencing (NGS). Results are analyzed with specialized HLA bioinformatics software and compared against the IPD-IMGT\/HLA database, which gives allele-level (high-resolution) typing and reduces the ambiguities that low- and intermediate-resolution methods leave.\u003cbr\u003eGenes Covered\u003c\/p\u003e\u003cp\u003eClass\tGenes\u003cbr\u003eClass I\tHLA-A, HLA-B, HLA-C\u003cbr\u003eClass II\tHLA-DRB1, HLA-DQB1, HLA-DPB1\u003c\/p\u003e","brand":"Enigma Genomics","offers":[{"title":"Default Title","offer_id":60790443966750,"sku":"EGHLAFULL","price":2800.0,"currency_code":"SAR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/6678\/6590\/files\/enigma-test-icon-general-genome-v1.png?v=1793571358","url":"https:\/\/shop.enigmagenomics.com\/en\/products\/eghlafull","provider":"Enigma Genomics","version":"1.0","type":"link"}