Colorectal Cancer Panel

The Colorectal Cancer Panel analyzes genes associated with a hereditary predisposition to colorectal cancer. These genes were selected based on the available evidence to date to provide the broadest test for colorectal cancer. In addition to the primary panel, several genes have been included to cover preliminary evidence for cancer predisposition. These genes were selected from a review of the literature and expert recommendations. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.