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Enigma Genomics
Homologous Recombination Deficiency by NGS - HRD
Homologous Recombination Deficiency by NGS - HRD
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Homologous Recombination Deficiency (HRD) analysis in somatic NGS detects genomic instability caused by defective DNA repair mechanisms. It identifies mutations in HRR pathway genes (e.g., BRCA1/2) and genomic scar signatures, aiding in predicting response to PARP inhibitors and DNA-damaging therapies.
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