Renal Tubular Disorders Panel

The Renal Tubular Disorders Panel analyzes genes that are associated with renal tubular disorders, which are characterized by impaired function and/or abnormal development of the renal tubules. These genes were selected based on the available evidence to date to provide a broad analysis of inherited renal tubular disorders. The genetic heterogeneity associated with these conditions can make it difficult to use phenotype as the sole criterion to select a definitive cause. Broad panel testing allows for an efficient evaluation of several potential genes based on a single clinical indication. Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant can inform recurrence-risk assessment and genetic counseling. Some genes in this test may be associated with additional disorders unrelated to this panel; such additional conditions are not included in the list of disorders tested.